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6gmb
From Proteopedia
(Difference between revisions)
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==Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate== | ==Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate== | ||
| - | <StructureSection load='6gmb' size='340' side='right' caption='[[6gmb]], [[Resolution|resolution]] 1.35Å' scene=''> | + | <StructureSection load='6gmb' size='340' side='right'caption='[[6gmb]], [[Resolution|resolution]] 1.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6gmb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMB OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6gmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GMB FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOA:GLYCOLIC+ACID'>GOA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOA:GLYCOLIC+ACID'>GOA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmb OCA], [https://pdbe.org/6gmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gmb RCSB], [https://www.ebi.ac.uk/pdbsum/6gmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmb ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. |
| + | |||
| + | ==See Also== | ||
| + | *[[Glycolate oxidase 3D structures|Glycolate oxidase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Arrowsmith | + | [[Category: Homo sapiens]] |
| - | [[Category: Bezerra | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Brennan | + | [[Category: Bezerra GA]] |
| - | [[Category: Edwards | + | [[Category: Bountra C]] |
| - | [[Category: Krojer | + | [[Category: Brennan PE]] |
| - | [[Category: MacKinnon | + | [[Category: Edwards E]] |
| - | [[Category: Oppermann | + | [[Category: Krojer T]] |
| - | + | [[Category: MacKinnon S]] | |
| - | [[Category: Smee | + | [[Category: Oppermann U]] |
| - | [[Category: Yue | + | [[Category: Smee C]] |
| - | + | [[Category: Yue WW]] | |
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Current revision
Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bezerra GA | Bountra C | Brennan PE | Edwards E | Krojer T | MacKinnon S | Oppermann U | Smee C | Yue WW
