1oa0

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[[Image:1oa0.jpg|left|200px]]
[[Image:1oa0.jpg|left|200px]]
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{{Structure
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|PDB= 1oa0 |SIZE=350|CAPTION= <scene name='initialview01'>1oa0</scene>, resolution 1.25&Aring;
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The line below this paragraph, containing "STRUCTURE_1oa0", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:Mes+Binding+Site+For+Chain+A'>AC1</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SF3:FE4-S3+CLUSTER'>SF3</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1oa0| PDB=1oa0 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oa0 OCA], [http://www.ebi.ac.uk/pdbsum/1oa0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1oa0 RCSB]</span>
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}}
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'''REDUCED HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO DESULFURICANS X-RAY STRUCTURE AT 1.25A RESOLUTION'''
'''REDUCED HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO DESULFURICANS X-RAY STRUCTURE AT 1.25A RESOLUTION'''
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[[Category: Teixeira, M.]]
[[Category: Teixeira, M.]]
[[Category: Xavier, A V.]]
[[Category: Xavier, A V.]]
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[[Category: desulfovibrio desulfurican]]
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[[Category: Desulfovibrio desulfurican]]
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[[Category: high-resolution]]
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[[Category: High-resolution]]
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[[Category: hybrid cluster]]
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[[Category: Hybrid cluster]]
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[[Category: reduced form]]
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[[Category: Reduced form]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:34:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:42:12 2008''
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Revision as of 00:34, 3 May 2008

Image:1oa0.jpg

Template:STRUCTURE 1oa0

REDUCED HYBRID CLUSTER PROTEIN FROM DESULFOVIBRIO DESULFURICANS X-RAY STRUCTURE AT 1.25A RESOLUTION


Overview

The hybrid cluster proteins from the sulfate reducing bacteria Desulfovibrio desulfuricans ATCC 27774 ( Dd) and Desulfovibrio vulgaris strain Hildenborough ( Dv) have been isolated and crystallized anaerobically. In each case, the protein has been reduced with dithionite and the crystal structure of the reduced form elucidated using X-ray synchrotron radiation techniques at 1.25 A and 1.55 A resolution for Dd and Dv, respectively. Although the overall structures of the proteins are unchanged upon reduction, there are significant changes at the hybrid cluster centres. These include significant movements in the position of the iron atom linked to the persulfide moiety in the oxidized as-isolated proteins and the sulfur atom of the persulfide itself. The nature of these changes is described and the implications with respect to the function of hybrid cluster proteins are discussed.

About this Structure

1OA0 is a Single protein structure of sequence from Desulfovibrio desulfuricans. Full crystallographic information is available from OCA.

Reference

Reduced hybrid cluster proteins (HCP) from Desulfovibrio desulfuricans ATCC 27774 and Desulfovibrio vulgaris (Hildenborough): X-ray structures at high resolution using synchrotron radiation., Aragao D, Macedo S, Mitchell EP, Romao CV, Liu MY, Frazao C, Saraiva LM, Xavier AV, LeGall J, van Dongen WM, Hagen WR, Teixeira M, Carrondo MA, Lindley P, J Biol Inorg Chem. 2003 May;8(5):540-8. Epub 2003 Feb 15. PMID:12764602 Page seeded by OCA on Sat May 3 03:34:35 2008

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