1oa1

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[[Image:1oa1.jpg|left|200px]]
[[Image:1oa1.jpg|left|200px]]
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{{Structure
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|PDB= 1oa1 |SIZE=350|CAPTION= <scene name='initialview01'>1oa1</scene>, resolution 1.55&Aring;
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The line below this paragraph, containing "STRUCTURE_1oa1", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Chain+A'>AC1</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF3:FE4-S3+CLUSTER'>SF3</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>
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{{STRUCTURE_1oa1| PDB=1oa1 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oa1 OCA], [http://www.ebi.ac.uk/pdbsum/1oa1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1oa1 RCSB]</span>
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'''REDUCED HYBRID CLUSTER PROTEIN (HCP) FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH STRUCTURE AT 1.55A RESOLUTION USING SYNCHROTRON RADIATION.'''
'''REDUCED HYBRID CLUSTER PROTEIN (HCP) FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH STRUCTURE AT 1.55A RESOLUTION USING SYNCHROTRON RADIATION.'''
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[[Category: Teixeira, M.]]
[[Category: Teixeira, M.]]
[[Category: Xavier, A V.]]
[[Category: Xavier, A V.]]
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[[Category: desulfovibrio vulgari]]
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[[Category: Desulfovibrio vulgari]]
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[[Category: hybrid cluster protein]]
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[[Category: Hybrid cluster protein]]
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[[Category: reduced form]]
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[[Category: Reduced form]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:34:48 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:42:08 2008''
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Revision as of 00:34, 3 May 2008

Image:1oa1.jpg

Template:STRUCTURE 1oa1

REDUCED HYBRID CLUSTER PROTEIN (HCP) FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH STRUCTURE AT 1.55A RESOLUTION USING SYNCHROTRON RADIATION.


Overview

The hybrid cluster proteins from the sulfate reducing bacteria Desulfovibrio desulfuricans ATCC 27774 ( Dd) and Desulfovibrio vulgaris strain Hildenborough ( Dv) have been isolated and crystallized anaerobically. In each case, the protein has been reduced with dithionite and the crystal structure of the reduced form elucidated using X-ray synchrotron radiation techniques at 1.25 A and 1.55 A resolution for Dd and Dv, respectively. Although the overall structures of the proteins are unchanged upon reduction, there are significant changes at the hybrid cluster centres. These include significant movements in the position of the iron atom linked to the persulfide moiety in the oxidized as-isolated proteins and the sulfur atom of the persulfide itself. The nature of these changes is described and the implications with respect to the function of hybrid cluster proteins are discussed.

About this Structure

1OA1 is a Single protein structure of sequence from Desulfovibrio vulgaris. Full crystallographic information is available from OCA.

Reference

Reduced hybrid cluster proteins (HCP) from Desulfovibrio desulfuricans ATCC 27774 and Desulfovibrio vulgaris (Hildenborough): X-ray structures at high resolution using synchrotron radiation., Aragao D, Macedo S, Mitchell EP, Romao CV, Liu MY, Frazao C, Saraiva LM, Xavier AV, LeGall J, van Dongen WM, Hagen WR, Teixeira M, Carrondo MA, Lindley P, J Biol Inorg Chem. 2003 May;8(5):540-8. Epub 2003 Feb 15. PMID:12764602 Page seeded by OCA on Sat May 3 03:34:48 2008

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