5n78

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Current revision (12:31, 15 November 2023) (edit) (undo)
 
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<StructureSection load='5n78' size='340' side='right'caption='[[5n78]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
<StructureSection load='5n78' size='340' side='right'caption='[[5n78]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5n78]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N78 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5N78 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5n78]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N78 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N78 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5n78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n78 OCA], [http://pdbe.org/5n78 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n78 RCSB], [http://www.ebi.ac.uk/pdbsum/5n78 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n78 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n78 OCA], [https://pdbe.org/5n78 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n78 RCSB], [https://www.ebi.ac.uk/pdbsum/5n78 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n78 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CORA_ECOLI CORA_ECOLI]] Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake (PubMed:780341). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity).[UniProtKB:Q9WZ31]<ref>PMID:780341</ref>
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[https://www.uniprot.org/uniprot/CORA_ECOLI CORA_ECOLI] Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake (PubMed:780341). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity).[UniProtKB:Q9WZ31]<ref>PMID:780341</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Flockner, L]]
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[[Category: Flockner L]]
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[[Category: Hogbom, M]]
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[[Category: Hogbom M]]
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[[Category: Lerche, M]]
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[[Category: Lerche M]]
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[[Category: Rapp, M]]
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[[Category: Rapp M]]
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[[Category: Sandhu, H]]
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[[Category: Sandhu H]]
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[[Category: Homopentamer complex transport membrane]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of the cytosolic domain of the CorA Mg2+ channel from Escherichia coli in complex with magnesium and cobalt hexammine

PDB ID 5n78

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