5n82

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:33, 15 November 2023) (edit) (undo)
 
Line 1: Line 1:
==Crystal structure of an engineered TycA variant in complex with an beta-Phe-AMP analog==
==Crystal structure of an engineered TycA variant in complex with an beta-Phe-AMP analog==
-
<StructureSection load='5n82' size='340' side='right' caption='[[5n82]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
+
<StructureSection load='5n82' size='340' side='right'caption='[[5n82]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5n82]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_10027 Atcc 10027]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N82 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N82 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5n82]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N82 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8PZ:[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl+~{N}-[(3~{S})-3-azanyl-3-phenyl-propanoyl]sulfamate'>8PZ</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.708&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tycA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=54914 ATCC 10027])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8PZ:[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl+~{N}-[(3~{S})-3-azanyl-3-phenyl-propanoyl]sulfamate'>8PZ</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_racemase_(ATP-hydrolyzing) Phenylalanine racemase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.11 5.1.1.11] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n82 OCA], [https://pdbe.org/5n82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n82 RCSB], [https://www.ebi.ac.uk/pdbsum/5n82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n82 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n82 OCA], [http://pdbe.org/5n82 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n82 RCSB], [http://www.ebi.ac.uk/pdbsum/5n82 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n82 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TYCA_BREPA TYCA_BREPA]] In the first step of peptide synthesis this enzyme activates phenylalanine and racemizes it to the D-isomer.
+
[https://www.uniprot.org/uniprot/TYCA_BREPA TYCA_BREPA] In the first step of peptide synthesis this enzyme activates phenylalanine and racemizes it to the D-isomer.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 10027]]
+
[[Category: Brevibacillus parabrevis]]
-
[[Category: Fercher, D]]
+
[[Category: Large Structures]]
-
[[Category: Hansen, D L]]
+
[[Category: Fercher D]]
-
[[Category: Hilvert, D]]
+
[[Category: Hansen DL]]
-
[[Category: Kries, H]]
+
[[Category: Hilvert D]]
-
[[Category: Mori, T]]
+
[[Category: Kries H]]
-
[[Category: Niquille, D L]]
+
[[Category: Mori T]]
-
[[Category: Adenylation domain]]
+
[[Category: Niquille DL]]
-
[[Category: Ligase]]
+
-
[[Category: Nonribosomal peptide synthetase]]
+

Current revision

Crystal structure of an engineered TycA variant in complex with an beta-Phe-AMP analog

PDB ID 5n82

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5n82"
Personal tools