5naz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:43, 15 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='5naz' size='340' side='right'caption='[[5naz]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='5naz' size='340' side='right'caption='[[5naz]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5naz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NAZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NAZ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5naz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NAZ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">COL4A5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5naz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5naz OCA], [http://pdbe.org/5naz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5naz RCSB], [http://www.ebi.ac.uk/pdbsum/5naz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5naz ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5naz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5naz OCA], [https://pdbe.org/5naz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5naz RCSB], [https://www.ebi.ac.uk/pdbsum/5naz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5naz ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/CO4A5_HUMAN CO4A5_HUMAN]] X-linked diffuse leiomyomatosis - Alport syndrome;X-linked Alport syndrome. The disease is caused by mutations affecting the gene represented in this entry. Deletions covering the N-terminal regions of COL4A5 and COL4A6, which are localized in a head-to-head manner, are found in the chromosome Xq22.3 centromeric deletion syndrome. This results in a phenotype with features of diffuse leiomyomatosis and Alport syndrome (DL-ATS).
+
[https://www.uniprot.org/uniprot/CO4A5_HUMAN CO4A5_HUMAN] X-linked diffuse leiomyomatosis - Alport syndrome;X-linked Alport syndrome. The disease is caused by mutations affecting the gene represented in this entry. Deletions covering the N-terminal regions of COL4A5 and COL4A6, which are localized in a head-to-head manner, are found in the chromosome Xq22.3 centromeric deletion syndrome. This results in a phenotype with features of diffuse leiomyomatosis and Alport syndrome (DL-ATS).
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CO4A5_HUMAN CO4A5_HUMAN]] Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
+
[https://www.uniprot.org/uniprot/CO4A5_HUMAN CO4A5_HUMAN] Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 28: Line 28:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Casino, P]]
+
[[Category: Casino P]]
-
[[Category: Marina, A]]
+
[[Category: Marina A]]
-
[[Category: Non-collagenous domain of collagen type iv. a principal structural component of basement membrane]]
+
-
[[Category: Structural protein]]
+

Current revision

Crystal structures of homooligomers of collagen type IV. alpha5NC1

PDB ID 5naz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools