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5nim

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Current revision (13:00, 15 November 2023) (edit) (undo)
 
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==EthR complex==
==EthR complex==
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<StructureSection load='5nim' size='340' side='right' caption='[[5nim]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='5nim' size='340' side='right'caption='[[5nim]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5nim]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NIM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NIM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5nim]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NIM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8YE:[1-(2-hydroxyethyl)pyrrolo[3,4-c]pyrazol-5-yl]-(5-propyl-1,2-oxazol-3-yl)methanone'>8YE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ethR, etaR, Rv3855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8YE:[1-(2-hydroxyethyl)pyrrolo[3,4-c]pyrazol-5-yl]-(5-propyl-1,2-oxazol-3-yl)methanone'>8YE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nim OCA], [http://pdbe.org/5nim PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nim RCSB], [http://www.ebi.ac.uk/pdbsum/5nim PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nim ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nim OCA], [https://pdbe.org/5nim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nim RCSB], [https://www.ebi.ac.uk/pdbsum/5nim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nim ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
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[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5nim" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5nim" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baulard, A R]]
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[[Category: Large Structures]]
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[[Category: Cole, J C]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Pohl, E]]
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[[Category: Baulard AR]]
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[[Category: Tatum, N J]]
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[[Category: Cole JC]]
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[[Category: Dna binding protein]]
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[[Category: Pohl E]]
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[[Category: Protein ligand complex]]
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[[Category: Tatum NJ]]
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[[Category: Tetr repressor]]
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Current revision

EthR complex

PDB ID 5nim

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