From Proteopedia
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| | + | '''Unreleased structure''' |
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| - | ==AtSLAC1 6D mutant in open state==
| + | The entry 8gw7 is ON HOLD until Paper Publication |
| - | <StructureSection load='8gw7' size='340' side='right'caption='[[8gw7]], [[Resolution|resolution]] 3.30Å' scene=''>
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| - | == Structural highlights ==
| + | Authors: Lee, Y., Lee, S. |
| - | <table><tr><td colspan='2'>[[8gw7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GW7 FirstGlance]. <br>
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| - | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr>
| + | Description: AtSLAC1 6D mutant in open state |
| - | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
| + | [[Category: Unreleased Structures]] |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gw7 OCA], [https://pdbe.org/8gw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gw7 RCSB], [https://www.ebi.ac.uk/pdbsum/8gw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gw7 ProSAT]</span></td></tr>
| + | [[Category: Lee, Y]] |
| - | </table>
| + | [[Category: Lee, S]] |
| - | == Function ==
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| - | [https://www.uniprot.org/uniprot/SLAC1_ARATH SLAC1_ARATH] Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis. Cl(-) efflux through SLAC1 causes membrane depolarization, which activates outward-rectifying K1 channels, leading to KCl and water efflux to reduce turgor further and cause stomatal closure, that reduces water loss and promotes leaf turgor. Essential for stomatal closure in response to CO(2), abscisic acid (ABA), ozone O(3), light/dark transitions, humidity change, calcium ions, hydrogen peroxide H(2)O(2), reactive oxygen species (ROS), and nitric oxide. Binds to the highly selective inward-rectifying potassium channels KAT1 and AKT2, and inhibits their activities. Functions as an essential negative regulator of inward potassium channels in guard cells. Essential for the efficient stomatal closure and opening in guard cells (PubMed:27002025). Involved in the local and/or systemic stomatal responses (e.g. stomatal closure) to light stress (PubMed:29463779).<ref>PMID:18084014</ref> <ref>PMID:18305482</ref> <ref>PMID:18305484</ref> <ref>PMID:19955405</ref> <ref>PMID:19955427</ref> <ref>PMID:20128877</ref> <ref>PMID:20345603</ref> <ref>PMID:27002025</ref> <ref>PMID:29463779</ref> <ref>PMID:18305482</ref> [https://www.uniprot.org/uniprot/A0A059PIQ0_AEQVI A0A059PIQ0_AEQVI]
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Arabidopsis thaliana]] | + | |
| - | [[Category: Large Structures]]
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| - | [[Category: Lee S]] | + | |
| - | [[Category: Lee Y]] | + | |
Revision as of 05:30, 22 November 2023
Unreleased structure
The entry 8gw7 is ON HOLD until Paper Publication
Authors: Lee, Y., Lee, S.
Description: AtSLAC1 6D mutant in open state
