8hib
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of Pygo2-LDB1-SSBP2 triple complex== |
| - | + | <StructureSection load='8hib' size='340' side='right'caption='[[8hib]], [[Resolution|resolution]] 2.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hib]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HIB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hib OCA], [https://pdbe.org/8hib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hib RCSB], [https://www.ebi.ac.uk/pdbsum/8hib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hib ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LDB1_HUMAN LDB1_HUMAN] Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Play a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wang HY]] | ||
| + | [[Category: Xu WQ]] | ||
| + | [[Category: Yan XX]] | ||
Revision as of 07:28, 22 November 2023
The crystal structure of Pygo2-LDB1-SSBP2 triple complex
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Categories: Homo sapiens | Large Structures | Wang HY | Xu WQ | Yan XX
