8uxg
From Proteopedia
(Difference between revisions)
m (Protected "8uxg" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210== | |
| - | + | <StructureSection load='8uxg' size='340' side='right'caption='[[8uxg]], [[Resolution|resolution]] 3.08Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8uxg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UXG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.08Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=KVR:4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic+acid'>KVR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uxg OCA], [https://pdbe.org/8uxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uxg RCSB], [https://www.ebi.ac.uk/pdbsum/8uxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uxg ProSAT]</span></td></tr> |
| - | [[Category: Marks | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FKB1B_HUMAN FKB1B_HUMAN] Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Marks AR]] | ||
| + | [[Category: Miotto MC]] | ||
Revision as of 07:35, 22 November 2023
Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210
| |||||||||||
