5xex

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Current revision (08:01, 22 November 2023) (edit) (undo)
 
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==Crystal structure of S.aureus PNPase catalytic domain==
==Crystal structure of S.aureus PNPase catalytic domain==
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<StructureSection load='5xex' size='340' side='right' caption='[[5xex]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='5xex' size='340' side='right'caption='[[5xex]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xex]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XEX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xex]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XEX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pnp, pnpA, SAOUHSC_01251 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93061 STAA8])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polyribonucleotide_nucleotidyltransferase Polyribonucleotide nucleotidyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.8 2.7.7.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xex OCA], [https://pdbe.org/5xex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xex RCSB], [https://www.ebi.ac.uk/pdbsum/5xex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xex ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xex OCA], [http://pdbe.org/5xex PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xex RCSB], [http://www.ebi.ac.uk/pdbsum/5xex PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xex ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PNP_STAA8 PNP_STAA8]] Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.[HAMAP-Rule:MF_01595]
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[https://www.uniprot.org/uniprot/PNP_STAA8 PNP_STAA8] Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.[HAMAP-Rule:MF_01595]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5xex" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5xex" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Polyribonucleotide nucleotidyltransferase]]
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[[Category: Large Structures]]
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[[Category: Staa8]]
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[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]]
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[[Category: Wang, X]]
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[[Category: Wang X]]
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[[Category: Zang, J]]
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[[Category: Zang J]]
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[[Category: Zhang, X]]
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[[Category: Zhang X]]
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[[Category: Catalytic domain]]
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[[Category: Polynucleotide phosphorylase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of S.aureus PNPase catalytic domain

PDB ID 5xex

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