5xox

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Current revision (08:08, 22 November 2023) (edit) (undo)
 
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<StructureSection load='5xox' size='340' side='right'caption='[[5xox]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='5xox' size='340' side='right'caption='[[5xox]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xox]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XOX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XOX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xox]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XOX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA(His)_guanylyltransferase tRNA(His) guanylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.79 2.7.7.79] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xox OCA], [http://pdbe.org/5xox PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xox RCSB], [http://www.ebi.ac.uk/pdbsum/5xox PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xox ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xox OCA], [https://pdbe.org/5xox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xox RCSB], [https://www.ebi.ac.uk/pdbsum/5xox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xox ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THG1_YEAST THG1_YEAST]] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.<ref>PMID:14633974</ref>
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[https://www.uniprot.org/uniprot/THG1_YEAST THG1_YEAST] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.<ref>PMID:14633974</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hwang, K Y]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Lee, E H]]
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[[Category: Hwang KY]]
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[[Category: Lee, K]]
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[[Category: Lee EH]]
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[[Category: Son, J]]
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[[Category: Lee K]]
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[[Category: Gtp]]
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[[Category: Son J]]
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[[Category: Post-transcriptional modification]]
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[[Category: Reverse polymerization]]
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[[Category: Thg1]]
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[[Category: Transferase]]
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Current revision

Crystal structure of tRNA(His) guanylyltranserase from Saccharomyces cerevisiae

PDB ID 5xox

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