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5xs0

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Current revision (08:11, 22 November 2023) (edit) (undo)
 
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==Structure of a ssDNA bound to the outer DNA binding site of RAD52==
==Structure of a ssDNA bound to the outer DNA binding site of RAD52==
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<StructureSection load='5xs0' size='340' side='right' caption='[[5xs0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='5xs0' size='340' side='right'caption='[[5xs0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xs0]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XS0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XS0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xs0]] is a 26 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XS0 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAD52 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xs0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xs0 OCA], [http://pdbe.org/5xs0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xs0 RCSB], [http://www.ebi.ac.uk/pdbsum/5xs0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xs0 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xs0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xs0 OCA], [https://pdbe.org/5xs0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xs0 RCSB], [https://www.ebi.ac.uk/pdbsum/5xs0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xs0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAD52_HUMAN RAD52_HUMAN]] Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.<ref>PMID:12379650</ref>
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[https://www.uniprot.org/uniprot/RAD52_HUMAN RAD52_HUMAN] Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.<ref>PMID:12379650</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Kagawa, W]]
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[[Category: Large Structures]]
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[[Category: Kurumizaka, H]]
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[[Category: Synthetic construct]]
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[[Category: Saito, K]]
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[[Category: Kagawa W]]
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[[Category: Saotome, M]]
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[[Category: Kurumizaka H]]
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[[Category: Sugiyama, S]]
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[[Category: Saito K]]
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[[Category: Yasuda, T]]
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[[Category: Saotome M]]
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[[Category: Dna repair protein]]
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[[Category: Sugiyama S]]
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[[Category: Protein-dna complex]]
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[[Category: Yasuda T]]
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[[Category: Recombination]]
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[[Category: Ssdna annealing protein]]
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Current revision

Structure of a ssDNA bound to the outer DNA binding site of RAD52

PDB ID 5xs0

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