5xsk

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==Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor==
==Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor==
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<StructureSection load='5xsk' size='340' side='right' caption='[[5xsk]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
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<StructureSection load='5xsk' size='340' side='right'caption='[[5xsk]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xsk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XSK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XSK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xsk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XSK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.84&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hdgf ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xsk OCA], [http://pdbe.org/5xsk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xsk RCSB], [http://www.ebi.ac.uk/pdbsum/5xsk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xsk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xsk OCA], [https://pdbe.org/5xsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xsk RCSB], [https://www.ebi.ac.uk/pdbsum/5xsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xsk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HDGF_RAT HDGF_RAT]] Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor (By similarity).
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[https://www.uniprot.org/uniprot/HDGF_RAT HDGF_RAT] Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
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[[Category: Escherichia coli BL21]]
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[[Category: Chen, C J]]
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[[Category: Large Structures]]
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[[Category: Chen, L Y]]
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[[Category: Rattus norvegicus]]
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[[Category: Hsieh, Y C]]
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[[Category: Chen CJ]]
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[[Category: Huang, Y C]]
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[[Category: Chen LY]]
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[[Category: Lin, P J]]
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[[Category: Hsieh YC]]
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[[Category: Growth factor]]
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[[Category: Huang YC]]
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[[Category: Hormone]]
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[[Category: Lin PJ]]

Current revision

Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor

PDB ID 5xsk

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