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5yjg

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Current revision (08:31, 22 November 2023) (edit) (undo)
 
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==Structural insights into periostin functions==
==Structural insights into periostin functions==
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<StructureSection load='5yjg' size='340' side='right' caption='[[5yjg]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='5yjg' size='340' side='right'caption='[[5yjg]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5yjg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YJG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YJG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5yjg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YJG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YJG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.399&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POSTN, OSF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yjg OCA], [http://pdbe.org/5yjg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yjg RCSB], [http://www.ebi.ac.uk/pdbsum/5yjg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yjg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yjg OCA], [https://pdbe.org/5yjg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yjg RCSB], [https://www.ebi.ac.uk/pdbsum/5yjg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yjg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/POSTN_HUMAN POSTN_HUMAN]] Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).[UniProtKB:Q62009]<ref>PMID:12235007</ref>
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[https://www.uniprot.org/uniprot/POSTN_HUMAN POSTN_HUMAN] Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007). Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).[UniProtKB:Q62009]<ref>PMID:12235007</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Liu, H]]
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[[Category: Large Structures]]
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[[Category: Liu, J]]
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[[Category: Liu H]]
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[[Category: Xu, F]]
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[[Category: Liu J]]
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[[Category: Cell adhesion]]
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[[Category: Xu F]]
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[[Category: Tissue regeneration]]
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Structural insights into periostin functions

PDB ID 5yjg

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