5yzw

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Current revision (08:42, 22 November 2023) (edit) (undo)
 
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<StructureSection load='5yzw' size='340' side='right'caption='[[5yzw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='5yzw' size='340' side='right'caption='[[5yzw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5yzw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_domesticus Mus domesticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YZW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5yzw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus_domesticus Mus musculus domesticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YZW FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ifi204 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10092 Mus domesticus])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.001&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yzw OCA], [https://pdbe.org/5yzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yzw RCSB], [https://www.ebi.ac.uk/pdbsum/5yzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yzw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yzw OCA], [https://pdbe.org/5yzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yzw RCSB], [https://www.ebi.ac.uk/pdbsum/5yzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yzw ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IFI4_MOUSE IFI4_MOUSE] Inhibits the transcription of ribosomal RNA. May inhibit DNA binding by UBTF. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways. Acts as a coactivator of RUNX2 during osteogenesis. May be involved in macrophage differentiation. Enables skeletal muscle and cardiac myocyte differentiation by sequestring Id proteins in the cytosol and promoting their ubiquitination and subsequent degradation.<ref>PMID:10329630</ref> <ref>PMID:11940648</ref> <ref>PMID:15557274</ref> <ref>PMID:16244109</ref> <ref>PMID:16458891</ref> <ref>PMID:16556595</ref> <ref>PMID:16556596</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mus domesticus]]
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[[Category: Mus musculus domesticus]]
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[[Category: Jin, T]]
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[[Category: Jin T]]
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[[Category: Dna sensor]]
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[[Category: Ifi204]]
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[[Category: Immune system]]
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[[Category: Interferon inducible gene 204]]
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[[Category: Pyhin family]]
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Current revision

Crystal structure of p204 HINb domain

PDB ID 5yzw

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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