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5ze4

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Current revision (08:52, 22 November 2023) (edit) (undo)
 
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==The structure of holo- structure of DHAD complex with [2Fe-2S] cluster==
==The structure of holo- structure of DHAD complex with [2Fe-2S] cluster==
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<StructureSection load='5ze4' size='340' side='right' caption='[[5ze4]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
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<StructureSection load='5ze4' size='340' side='right'caption='[[5ze4]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ze4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZE4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ze4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZE4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DHAD, ILVD, At3g23940, F14O13.13 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lyase Lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.9 4.2.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ze4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ze4 OCA], [https://pdbe.org/5ze4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ze4 RCSB], [https://www.ebi.ac.uk/pdbsum/5ze4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ze4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ze4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ze4 OCA], [http://pdbe.org/5ze4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ze4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ze4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ze4 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ILVD_ARATH ILVD_ARATH]] Catalyzes the dehydration of 2,3-dihydroxy-3-isovalerate or 2,3-dihydroxy-3-methylvalerate to the 2-oxo acids 3-methyl-2-oxobutanoate (3MOB) or 3-methyl-2-oxopentanoate (3MOP).<ref>PMID:12242394</ref>
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[https://www.uniprot.org/uniprot/ILVD_ARATH ILVD_ARATH] Catalyzes the dehydration of 2,3-dihydroxy-3-isovalerate or 2,3-dihydroxy-3-methylvalerate to the 2-oxo acids 3-methyl-2-oxobutanoate (3MOB) or 3-methyl-2-oxopentanoate (3MOP).<ref>PMID:12242394</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Lyase]]
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[[Category: Large Structures]]
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[[Category: Gan, J]]
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[[Category: Gan J]]
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[[Category: Tang, Y]]
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[[Category: Tang Y]]
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[[Category: Wu, L]]
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[[Category: Wu L]]
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[[Category: Yan, Y]]
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[[Category: Yan Y]]
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[[Category: Zang, X]]
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[[Category: Zang X]]
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[[Category: Zhou, J]]
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[[Category: Zhou J]]
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[[Category: Bcaabiosynthetic pathway]]
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[[Category: Inhibit]]
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The structure of holo- structure of DHAD complex with [2Fe-2S] cluster

PDB ID 5ze4

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