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5zh2

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Current revision (08:54, 22 November 2023) (edit) (undo)
 
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==CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-5==
==CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-5==
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<StructureSection load='5zh2' size='340' side='right' caption='[[5zh2]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
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<StructureSection load='5zh2' size='340' side='right'caption='[[5zh2]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5zh2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafo Plafo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZH2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5zh2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_NF54 Plasmodium falciparum NF54]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZH2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9CU:(3R)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one'>9CU</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=MPO:3[N-MORPHOLINO]PROPANE+SULFONIC+ACID'>MPO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.66&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFNF54_04763 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5843 PLAFO])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9CU:(3R)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one'>9CU</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=MPO:3[N-MORPHOLINO]PROPANE+SULFONIC+ACID'>MPO</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysine--tRNA_ligase Lysine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.6 6.1.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zh2 OCA], [https://pdbe.org/5zh2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zh2 RCSB], [https://www.ebi.ac.uk/pdbsum/5zh2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zh2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zh2 OCA], [http://pdbe.org/5zh2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zh2 RCSB], [http://www.ebi.ac.uk/pdbsum/5zh2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zh2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/W7JP72_PLAFO W7JP72_PLAFO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5zh2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5zh2" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lysine--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Plafo]]
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[[Category: Plasmodium falciparum NF54]]
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[[Category: Babbar, P]]
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[[Category: Babbar P]]
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[[Category: Harlos, K]]
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[[Category: Harlos K]]
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[[Category: Malhotra, N]]
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[[Category: Malhotra N]]
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[[Category: Manickam, Y]]
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[[Category: Manickam Y]]
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[[Category: Reddy, D S]]
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[[Category: Reddy DS]]
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[[Category: Sharma, A]]
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[[Category: Sharma A]]
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[[Category: Sharma, M]]
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[[Category: Sharma M]]
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[[Category: Kr]]
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[[Category: Ligase]]
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[[Category: Ligase-ligase inhibitor complex]]
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Current revision

CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-5

PDB ID 5zh2

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