6acx

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Current revision (09:26, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6acx' size='340' side='right'caption='[[6acx]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
<StructureSection load='6acx' size='340' side='right'caption='[[6acx]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6acx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ACX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ACX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6acx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ACX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ACX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ac6|6ac6]], [[6ac8|6ac8]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6acx OCA], [http://pdbe.org/6acx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6acx RCSB], [http://www.ebi.ac.uk/pdbsum/6acx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6acx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6acx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6acx OCA], [https://pdbe.org/6acx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6acx RCSB], [https://www.ebi.ac.uk/pdbsum/6acx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6acx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/I7G7M2_MYCS2 I7G7M2_MYCS2]] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.[HAMAP-Rule:MF_00969]
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[https://www.uniprot.org/uniprot/A0R3C5_MYCS2 A0R3C5_MYCS2] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.[HAMAP-Rule:MF_00969]
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==See Also==
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*[[Transcription-repair coupling factor 3D structures|Transcription-repair coupling factor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fox, G C]]
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[[Category: Mycolicibacterium smegmatis MC2 155]]
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[[Category: Nagaraja, V]]
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[[Category: Fox GC]]
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[[Category: Natesh, R]]
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[[Category: Nagaraja V]]
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[[Category: Putta, S]]
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[[Category: Natesh R]]
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[[Category: Rao, D N]]
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[[Category: Putta S]]
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[[Category: Walsh, M A]]
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[[Category: Rao DN]]
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[[Category: Hydrolase]]
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[[Category: Walsh MA]]
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[[Category: Mfd]]
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[[Category: Transcription coupled nucleotide excision repair]]
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[[Category: Transcription regulation]]
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[[Category: Transcription repair coupling factor]]
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Current revision

Crystal structure of Mycobacterium smegmatis Mfd in complex with ADP + Pi at 3.5 A resolution.

PDB ID 6acx

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