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6ai7

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Current revision (09:31, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6ai7' size='340' side='right'caption='[[6ai7]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
<StructureSection load='6ai7' size='340' side='right'caption='[[6ai7]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ai7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AI7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ai7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AI7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9Q6:1-deoxy-1-[(4aS)-4a-hydroxy-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-5-O-phosphono-D-ribitol'>9Q6</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxymandelate_oxidase 4-hydroxymandelate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.46 1.1.3.46] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9Q6:1-deoxy-1-[(4aS)-4a-hydroxy-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-5-O-phosphono-D-ribitol'>9Q6</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ai7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ai7 OCA], [http://pdbe.org/6ai7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ai7 RCSB], [http://www.ebi.ac.uk/pdbsum/6ai7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ai7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ai7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ai7 OCA], [https://pdbe.org/6ai7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ai7 RCSB], [https://www.ebi.ac.uk/pdbsum/6ai7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ai7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HMO_AMYOR HMO_AMYOR]] Catalyzes the oxidation of p-hydroxymandelate to p-hydroxybenzoylformate in the biosynthesis of L-(4-hydroxyphenyl)glycine and L-(3,5-dihydroxyphenyl)glycine, 2 non-proteinogenic amino acids occurring in the vancomycin group of antibiotics.<ref>PMID:11137816</ref> <ref>PMID:12240298</ref>
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[https://www.uniprot.org/uniprot/HMO_AMYOR HMO_AMYOR] Catalyzes the oxidation of p-hydroxymandelate to p-hydroxybenzoylformate in the biosynthesis of L-(4-hydroxyphenyl)glycine and L-(3,5-dihydroxyphenyl)glycine, 2 non-proteinogenic amino acids occurring in the vancomycin group of antibiotics.<ref>PMID:11137816</ref> <ref>PMID:12240298</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 4-hydroxymandelate oxidase]]
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[[Category: Amycolatopsis orientalis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Li, T L]]
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[[Category: Li TL]]
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[[Category: Lin, K H]]
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[[Category: Lin KH]]
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[[Category: Flavoprotein]]
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[[Category: Fmn-dependent oxidase]]
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Current revision

Mandelate oxidase mutant-Y128F with the C4a-OH-FMN adduct

PDB ID 6ai7

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