6aif

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Current revision (09:31, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6aif' size='340' side='right'caption='[[6aif]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='6aif' size='340' side='right'caption='[[6aif]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6aif]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AIF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6AIF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6aif]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20] and [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AIF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AIF FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_synthase Cysteine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.47 2.5.1.47] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6aif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aif OCA], [http://pdbe.org/6aif PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aif RCSB], [http://www.ebi.ac.uk/pdbsum/6aif PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aif ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aif OCA], [https://pdbe.org/6aif PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aif RCSB], [https://www.ebi.ac.uk/pdbsum/6aif PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aif ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYSK_HAEIN CYSK_HAEIN]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cysteine synthase]]
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[[Category: Haemophilus influenzae Rd KW20]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kaushik, A]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Singh, R P]]
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[[Category: Kaushik A]]
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[[Category: Cysk m120 mutant]]
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[[Category: Singh RP]]
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[[Category: Cysk/peptide inhibitor]]
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[[Category: O-acetylserine sulfhydrylase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Crystal structure of M120A mutant of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high affinity inhibitory peptide from serine acetyl transferase of Salmonella typhimurium

PDB ID 6aif

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