6ajc

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Current revision (09:32, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6ajc' size='340' side='right'caption='[[6ajc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='6ajc' size='340' side='right'caption='[[6ajc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ajc]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AJC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AJC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ajc]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AJC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ajc OCA], [http://pdbe.org/6ajc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ajc RCSB], [http://www.ebi.ac.uk/pdbsum/6ajc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ajc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ajc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ajc OCA], [https://pdbe.org/6ajc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ajc RCSB], [https://www.ebi.ac.uk/pdbsum/6ajc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ajc ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4E4L7_TRYCC Q4E4L7_TRYCC]
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==See Also==
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*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Allman, S]]
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[[Category: Trypanosoma cruzi strain CL Brener]]
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[[Category: Balogun, E O]]
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[[Category: Allman S]]
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[[Category: Boshart, M]]
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[[Category: Balogun EO]]
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[[Category: Bringaud, F]]
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[[Category: Boshart M]]
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[[Category: Harada, S]]
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[[Category: Bringaud F]]
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[[Category: Inaoka, D K]]
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[[Category: Harada S]]
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[[Category: Kita, K]]
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[[Category: Inaoka DK]]
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[[Category: Nozaki, T]]
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[[Category: Kita K]]
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[[Category: Shiba, T]]
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[[Category: Nozaki T]]
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[[Category: Wang, X]]
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[[Category: Shiba T]]
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[[Category: Watanabe, Y]]
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[[Category: Wang X]]
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[[Category: Ziebart, N]]
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[[Category: Watanabe Y]]
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[[Category: Isocitrate dehydrogenase]]
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[[Category: Ziebart N]]
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[[Category: Metabolism]]
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[[Category: Oxidoreductase]]
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[[Category: Trypanosoma cruzi]]
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Current revision

Crystal structure of Trypanosoma cruzi cytosolic isocitrate dehydrogenase in complex with NADP+, isocitrate and ca2+

PDB ID 6ajc

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