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6iis

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Current revision (09:43, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6iis' size='340' side='right'caption='[[6iis]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
<StructureSection load='6iis' size='340' side='right'caption='[[6iis]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6iis]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IIS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6iis]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IIS FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.358&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6iip|6iip]], [[6iiq|6iiq]], [[6iir|6iir]], [[6iit|6iit]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iis OCA], [http://pdbe.org/6iis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iis RCSB], [http://www.ebi.ac.uk/pdbsum/6iis PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iis ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iis OCA], [https://pdbe.org/6iis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iis RCSB], [https://www.ebi.ac.uk/pdbsum/6iis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iis ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HDGR3_HUMAN HDGR3_HUMAN]] Enhances DNA synthesis and may play a role in cell proliferation.<ref>PMID:10581169</ref>
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[https://www.uniprot.org/uniprot/HDGR3_HUMAN HDGR3_HUMAN] Enhances DNA synthesis and may play a role in cell proliferation.<ref>PMID:10581169</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tian, W]]
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[[Category: Synthetic construct]]
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[[Category: Wang, Z]]
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[[Category: Tian W]]
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[[Category: Dna binding protein]]
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[[Category: Wang Z]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Growth factor]]
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[[Category: Hepatoma-derived growth factor-related protein 3]]
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[[Category: Pwwp domain]]
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Current revision

Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and an H3K36me3-containing histone peptide

PDB ID 6iis

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