6ixq

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Current revision (09:54, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6ixq' size='340' side='right'caption='[[6ixq]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
<StructureSection load='6ixq' size='340' side='right'caption='[[6ixq]], [[Resolution|resolution]] 3.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ixq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IXQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ixq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IXQ FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYO2, CDC66, YOR326W, O6167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), SMY1, YKL079W, YKL409 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.06&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ixq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixq OCA], [http://pdbe.org/6ixq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ixq RCSB], [http://www.ebi.ac.uk/pdbsum/6ixq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixq ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ixq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixq OCA], [https://pdbe.org/6ixq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ixq RCSB], [https://www.ebi.ac.uk/pdbsum/6ixq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYO2_YEAST MYO2_YEAST]] Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Essential for the delivery of secretory vesicles to sites of active growth during bud emergence and cytokinesis. Required for segregation and inheritance of peroxisomes, late Golgi compartments, mitochondria and the vacuole to the daughter cell during cell division. Also required for correct alignment of the spindle during mitosis.<ref>PMID:10931864</ref> <ref>PMID:11285273</ref> <ref>PMID:11381095</ref> <ref>PMID:11733545</ref> <ref>PMID:11781333</ref> <ref>PMID:12391144</ref> <ref>PMID:12743102</ref> <ref>PMID:21248204</ref> [[http://www.uniprot.org/uniprot/SMY1_YEAST SMY1_YEAST]] Possible microtubule-based motor that can interact or substitute with myosin 2 (MYO2).
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[https://www.uniprot.org/uniprot/MYO2_YEAST MYO2_YEAST] Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Essential for the delivery of secretory vesicles to sites of active growth during bud emergence and cytokinesis. Required for segregation and inheritance of peroxisomes, late Golgi compartments, mitochondria and the vacuole to the daughter cell during cell division. Also required for correct alignment of the spindle during mitosis.<ref>PMID:10931864</ref> <ref>PMID:11285273</ref> <ref>PMID:11381095</ref> <ref>PMID:11733545</ref> <ref>PMID:11781333</ref> <ref>PMID:12391144</ref> <ref>PMID:12743102</ref> <ref>PMID:21248204</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6ixq" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ixq" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Myosin 3D Structures|Myosin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tang, K]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Wei, Z]]
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[[Category: Tang K]]
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[[Category: Cargo binding domain]]
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[[Category: Wei Z]]
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[[Category: Protein binding]]
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Current revision

Structure of Myo2-GTD in complex with Smy1

PDB ID 6ixq

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