6j4g

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Current revision (09:59, 22 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6j4g is ON HOLD until Paper Publication
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==Crystal structure of the AtWRKY33 domain==
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<StructureSection load='6j4g' size='340' side='right'caption='[[6j4g]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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Authors: Xu, Y.P., Xu, H., Wang, B., Su, X.D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6j4g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J4G FirstGlance]. <br>
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Description: Crystal structure of the AtWRKY33 domain
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Wang, B]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j4g OCA], [https://pdbe.org/6j4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j4g RCSB], [https://www.ebi.ac.uk/pdbsum/6j4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j4g ProSAT]</span></td></tr>
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[[Category: Xu, H]]
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</table>
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[[Category: Xu, Y.P]]
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== Function ==
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[[Category: Su, X.D]]
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[https://www.uniprot.org/uniprot/WRK33_ARATH WRK33_ARATH] Transcription factor. Interacts specifically with the W box (5'-TTGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Involved in defense responses. Required for resistance to the necrotrophic fungal pathogen B.cinerea (PubMed:17059405, PubMed:21990940). Regulates the antagonistic relationship between defense pathways mediating responses to the bacterial pathogen P. syringae and the necrotrophic pathogen B.cinerea (PubMed:17059405). Required for the phytoalexin camalexin synthesis following infection with B.cinerea. Acts as positive regulator of the camalexin biosynthetic genes PAD3 (CYP71B15) and CYP71A13 by binding to their promoters (PubMed:21498677, PubMed:22392279). Acts downstream of MPK3 and MPK6 in reprogramming the expression of camalexin biosynthetic genes, which drives the metabolic flow to camalexin production (PubMed:21498677). Functions with WRKY25 as positive regulator of salt stress response and abscisic acid (ABA) signaling (PubMed:18839316). Functions with WRKY25 and WRKY26 as positive regulator of plant thermotolerance by partially participating in ethylene-response signal transduction pathway (PubMed:21336597). The DNA-binding activity of WRKY33 is increased by SIB1 and SIB2 (PubMed:21990940).<ref>PMID:18839316</ref> <ref>PMID:21336597</ref> <ref>PMID:21498677</ref> <ref>PMID:21990940</ref> <ref>PMID:22392279</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Large Structures]]
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[[Category: Su XD]]
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[[Category: Wang B]]
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[[Category: Xu H]]
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[[Category: Xu YP]]

Current revision

Crystal structure of the AtWRKY33 domain

PDB ID 6j4g

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