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6j64

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Current revision (10:01, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6j64' size='340' side='right'caption='[[6j64]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
<StructureSection load='6j64' size='340' side='right'caption='[[6j64]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6j64]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J64 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6J64 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6j64]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J64 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B4P:BIS(ADENOSINE)-5-TETRAPHOSPHATE'>B4P</scene>, <scene name='pdbligand=TAU:2-AMINOETHANESULFONIC+ACID'>TAU</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ed3|5ed3]], [[5ed6|5ed6]], [[6j53|6j53]], [[6j58|6j58]], [[6j5s|6j5s]], [[6j5z|6j5z]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B4P:BIS(ADENOSINE)-5-TETRAPHOSPHATE'>B4P</scene>, <scene name='pdbligand=TAU:2-AMINOETHANESULFONIC+ACID'>TAU</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HINT1, HINT, PKCI1, PRKCNH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j64 OCA], [https://pdbe.org/6j64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j64 RCSB], [https://www.ebi.ac.uk/pdbsum/6j64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j64 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6j64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j64 OCA], [http://pdbe.org/6j64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j64 RCSB], [http://www.ebi.ac.uk/pdbsum/6j64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j64 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
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[https://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6j64" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6j64" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histidine triad nucleotide-binding protein 3D structures|Histidine triad nucleotide-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fang, P]]
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[[Category: Fang P]]
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[[Category: Guo, M]]
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[[Category: Guo M]]
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[[Category: Wang, J]]
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[[Category: Wang J]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide binding]]
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[[Category: Regulation of transcription]]
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[[Category: Signal transduction]]
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Current revision

Crystal structure of human HINT1 mutant complexing with AP4A

PDB ID 6j64

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