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6k1r

From Proteopedia

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Current revision (10:25, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6k1r' size='340' side='right'caption='[[6k1r]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='6k1r' size='340' side='right'caption='[[6k1r]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6k1r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K1R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K1R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6k1r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K1R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K1R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KPL:KETOPANTOATE'>KPL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">panE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KPL:KETOPANTOATE'>KPL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k1r OCA], [https://pdbe.org/6k1r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k1r RCSB], [https://www.ebi.ac.uk/pdbsum/6k1r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k1r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k1r OCA], [https://pdbe.org/6k1r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k1r RCSB], [https://www.ebi.ac.uk/pdbsum/6k1r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k1r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PANE_PSEAE PANE_PSEAE]] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
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[https://www.uniprot.org/uniprot/PANE_PSEAE PANE_PSEAE] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-dehydropantoate 2-reductase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseae]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Choudhury, A]]
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[[Category: Choudhury A]]
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[[Category: Datta, S]]
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[[Category: Datta S]]
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[[Category: Khanppnavar, B]]
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[[Category: Khanppnavar B]]
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[[Category: Oxidoreductase]]
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[[Category: Redox cofactor]]
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[[Category: Vitamin b5 biosynthesis pathway]]
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Current revision

Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa in complex with NAD+ and ketopantoate

PDB ID 6k1r

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