6l8z

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Current revision (10:53, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6l8z' size='340' side='right'caption='[[6l8z]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='6l8z' size='340' side='right'caption='[[6l8z]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6l8z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6L8Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6l8z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Siraitia_grosvenorii Siraitia grosvenorii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6L8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6L8Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6l8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l8z OCA], [http://pdbe.org/6l8z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6l8z RCSB], [http://www.ebi.ac.uk/pdbsum/6l8z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6l8z ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6l8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6l8z OCA], [https://pdbe.org/6l8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6l8z RCSB], [https://www.ebi.ac.uk/pdbsum/6l8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6l8z ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/74AC1_SIRGR 74AC1_SIRGR] Catalyzes the transfer of a glucose moiety to the C-3 hydroxyl of mogrol to form mogroside IE (PubMed:25759326, Ref.3). Besides mogrol, UGT74AC1 also shows activity in vitro with quercetin and naringenin as substrate (PubMed:25759326).<ref>PMID:25759326</ref> <ref>PMID:25759326</ref>
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==See Also==
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Li, J]]
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[[Category: Siraitia grosvenorii]]
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[[Category: Liu, W D]]
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[[Category: Li J]]
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[[Category: Shan, N]]
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[[Category: Liu WD]]
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[[Category: Sun, Y X]]
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[[Category: Shan N]]
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[[Category: Yang, J G]]
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[[Category: Sun YX]]
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[[Category: Transferase]]
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[[Category: Yang JG]]

Current revision

Crystal structure of ugt transferase mutant in complex with UPG

PDB ID 6l8z

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