6lf7
From Proteopedia
(Difference between revisions)
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<StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution|resolution]] 1.79Å' scene=''> | <StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution|resolution]] 1.79Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4n7a 4n7a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LF7 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.794Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [https://pdbe.org/6lf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [https://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref> |
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| + | ==See Also== | ||
| + | *[[Lactoperoxidase|Lactoperoxidase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Capra hircus]] | [[Category: Capra hircus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Bhushan A]] | |
| - | [[Category: Bhushan | + | [[Category: Kaur P]] |
| - | [[Category: Kaur | + | [[Category: Sharma S]] |
| - | [[Category: Sharma | + | [[Category: Singh A]] |
| - | [[Category: Singh | + | [[Category: Singh AK]] |
| - | [[Category: Singh | + | [[Category: Singh RP]] |
| - | [[Category: Singh | + | [[Category: Singh TP]] |
| - | [[Category: Singh | + | [[Category: Sinha M]] |
| - | [[Category: Sinha | + | [[Category: Tyagi TK]] |
| - | [[Category: Tyagi | + | [[Category: Viswanathan V]] |
| - | [[Category: Viswanathan | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.
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Categories: Capra hircus | Large Structures | Bhushan A | Kaur P | Sharma S | Singh A | Singh AK | Singh RP | Singh TP | Sinha M | Tyagi TK | Viswanathan V
