This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6lf7
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution|resolution]] 1.79Å' scene=''> | <StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution|resolution]] 1.79Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4n7a 4n7a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LF7 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.794Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [https://pdbe.org/6lf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [https://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Lactoperoxidase|Lactoperoxidase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 16: | Line 19: | ||
[[Category: Capra hircus]] | [[Category: Capra hircus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Bhushan A]] | |
| - | [[Category: Bhushan | + | [[Category: Kaur P]] |
| - | [[Category: Kaur | + | [[Category: Sharma S]] |
| - | [[Category: Sharma | + | [[Category: Singh A]] |
| - | [[Category: Singh | + | [[Category: Singh AK]] |
| - | [[Category: Singh | + | [[Category: Singh RP]] |
| - | [[Category: Singh | + | [[Category: Singh TP]] |
| - | [[Category: Singh | + | [[Category: Sinha M]] |
| - | [[Category: Sinha | + | [[Category: Tyagi TK]] |
| - | [[Category: Tyagi | + | [[Category: Viswanathan V]] |
| - | [[Category: Viswanathan | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.
| |||||||||||
Categories: Capra hircus | Large Structures | Bhushan A | Kaur P | Sharma S | Singh A | Singh AK | Singh RP | Singh TP | Sinha M | Tyagi TK | Viswanathan V
