1oia
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1oia.gif|left|200px]] | [[Image:1oia.gif|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1oia", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | | | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), |
| - | | | + | or leave the SCENE parameter empty for the default display. |
| - | + | --> | |
| - | + | {{STRUCTURE_1oia| PDB=1oia | SCENE= }} | |
| - | + | ||
| - | + | ||
| - | }} | + | |
'''U1A RNP DOMAIN 1-95''' | '''U1A RNP DOMAIN 1-95''' | ||
| Line 19: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1OIA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry | + | 1OIA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1nrc 1nrc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OIA OCA]. |
==Reference== | ==Reference== | ||
| Line 27: | Line 24: | ||
[[Category: Evans, P R.]] | [[Category: Evans, P R.]] | ||
[[Category: Nagai, K.]] | [[Category: Nagai, K.]] | ||
| - | [[Category: | + | [[Category: Nuclear protein]] |
| - | [[Category: | + | [[Category: Ribonucleoprotein]] |
| - | [[Category: | + | [[Category: Rna-binding]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:52:46 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 00:52, 3 May 2008
U1A RNP DOMAIN 1-95
Overview
The crystal structure of the RNA binding domain of the U1 small nuclear ribonucleoprotein A, which forms part of the ribonucleoprotein complex involved in the excision of introns, has been solved. It contains a four-stranded beta sheet and two alpha helices. The highly conserved segments designated RNP1 and RNP2 lie side by side on the middle two beta strands. U1 RNA binding studies of mutant proteins suggest that the RNA binds to the four-stranded beta sheet and to the flexible loops on one end.
About this Structure
1OIA is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1nrc. Full crystallographic information is available from OCA.
Reference
Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A., Nagai K, Oubridge C, Jessen TH, Li J, Evans PR, Nature. 1990 Dec 6;348(6301):515-20. PMID:2147232 Page seeded by OCA on Sat May 3 03:52:46 2008
