8ofa

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'''Unreleased structure'''
 
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The entry 8ofa is ON HOLD until 2024-09-14
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==Crystal structure of human cathepsin L interacting with tosyl phenylalanyl chloromethyl ketone (TPCK)==
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<StructureSection load='8ofa' size='340' side='right'caption='[[8ofa]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ofa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OFA FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=TQ8:N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]-4-METHYL-BENZENESULFONAMIDE'>TQ8</scene>, <scene name='pdbligand=VLF:4-methyl-~{N}-[(2~{S})-4-oxidanyl-3-oxidanylidene-1-phenyl-butan-2-yl]benzenesulfonamide'>VLF</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ofa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ofa OCA], [https://pdbe.org/8ofa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ofa RCSB], [https://www.ebi.ac.uk/pdbsum/8ofa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ofa ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chapman HN]]
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[[Category: Ewert W]]
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[[Category: Falke S]]
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[[Category: Guenther S]]
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[[Category: Hinrichs W]]
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[[Category: Karnicar K]]
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[[Category: Lieske J]]
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[[Category: Lindic N]]
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[[Category: Loboda J]]
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[[Category: Meents A]]
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[[Category: Reinke PYA]]
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[[Category: Sekirnik A]]
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[[Category: Turk D]]
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[[Category: Usenik A]]

Revision as of 13:59, 29 November 2023

Crystal structure of human cathepsin L interacting with tosyl phenylalanyl chloromethyl ketone (TPCK)

PDB ID 8ofa

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