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6ltv

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Current revision (14:52, 29 November 2023) (edit) (undo)
 
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<StructureSection load='6ltv' size='340' side='right'caption='[[6ltv]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
<StructureSection load='6ltv' size='340' side='right'caption='[[6ltv]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6ltv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryho Cryho]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LTV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6LTV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6ltv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LTV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=EU9:[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[(3R)-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]-[(2-nitrophenyl)methyl]sulfanium'>EU9</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHUDEA7_2650 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237895 CRYHO])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=EU9:[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[(3R)-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]-[(2-nitrophenyl)methyl]sulfanium'>EU9</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ltv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ltv OCA], [https://pdbe.org/6ltv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ltv RCSB], [https://www.ebi.ac.uk/pdbsum/6ltv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ltv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ltv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ltv OCA], [http://pdbe.org/6ltv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ltv RCSB], [http://www.ebi.ac.uk/pdbsum/6ltv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ltv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0S4TKQ5_CRYHO A0A0S4TKQ5_CRYHO]] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.[RuleBase:RU000541]
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[https://www.uniprot.org/uniprot/A0A0S4TKQ5_CRYHO A0A0S4TKQ5_CRYHO] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.[RuleBase:RU000541]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6ltv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6ltv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cryho]]
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[[Category: Cryptosporidium hominis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Methionine adenosyltransferase]]
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[[Category: Kuemmel D]]
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[[Category: Kuemmel, D]]
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[[Category: Michailidou F]]
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[[Category: Michailidou, F]]
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[[Category: Rentmeister A]]
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[[Category: Rentmeister, A]]
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[[Category: Singh RK]]
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[[Category: Singh, R K]]
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[[Category: S-adenosylmethionine synthetase]]
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[[Category: Transferase]]
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[[Category: Triphosphate]]
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Current revision

Crystal Structure of I122A/I330A variant of S-adenosylmethionine synthetase from Cryptosporidium hominis in complex with ONB-SAM (2-nitro benzyme S-adenosyl-methionine)

PDB ID 6ltv

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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