7cvp

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Current revision (16:17, 29 November 2023) (edit) (undo)
 
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==The Crystal Structure of human PHGDH from Biortus.==
==The Crystal Structure of human PHGDH from Biortus.==
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<StructureSection load='7cvp' size='340' side='right'caption='[[7cvp]]' scene=''>
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<StructureSection load='7cvp' size='340' side='right'caption='[[7cvp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CVP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CVP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7cvp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CVP FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cvp OCA], [http://pdbe.org/7cvp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cvp RCSB], [http://www.ebi.ac.uk/pdbsum/7cvp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cvp ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cvp OCA], [https://pdbe.org/7cvp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cvp RCSB], [https://www.ebi.ac.uk/pdbsum/7cvp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cvp ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/SERA_HUMAN SERA_HUMAN] Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:[https://omim.org/entry/601815 601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures.
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== Function ==
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[https://www.uniprot.org/uniprot/SERA_HUMAN SERA_HUMAN]
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==See Also==
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*[[Phosphoglycerate dehydrogenase|Phosphoglycerate dehydrogenase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cheng W]]
[[Category: Cheng W]]

Current revision

The Crystal Structure of human PHGDH from Biortus.

PDB ID 7cvp

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