7dc9

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Current revision (16:30, 29 November 2023) (edit) (undo)
 
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<StructureSection load='7dc9' size='340' side='right'caption='[[7dc9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='7dc9' size='340' side='right'caption='[[7dc9]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7dc9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DC9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7dc9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DC9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Guanosine_deaminase Guanosine deaminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.15 3.5.4.15] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dc9 OCA], [https://pdbe.org/7dc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dc9 RCSB], [https://www.ebi.ac.uk/pdbsum/7dc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dc9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dc9 OCA], [https://pdbe.org/7dc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dc9 RCSB], [https://www.ebi.ac.uk/pdbsum/7dc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dc9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/GSDA_ARATH GSDA_ARATH]] Catalyzes the hydrolytic deamination of guanosine, producing xanthosine and ammonia. Deaminates exclusively guanosine and 2'-deoxyguanosine but no other aminated purines, pyrimidines, or pterines. Deamination of guanosine by GSDA is the only source of xanthosine production in Arabidopsis.<ref>PMID:24130159</ref>
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[https://www.uniprot.org/uniprot/GSDA_ARATH GSDA_ARATH] Catalyzes the hydrolytic deamination of guanosine, producing xanthosine and ammonia. Deaminates exclusively guanosine and 2'-deoxyguanosine but no other aminated purines, pyrimidines, or pterines. Deamination of guanosine by GSDA is the only source of xanthosine production in Arabidopsis.<ref>PMID:24130159</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7dc9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7dc9" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Deaminase 3D structures|Deaminase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Guanosine deaminase]]
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[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Jia, Q]]
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[[Category: Jia Q]]
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[[Category: Xie, W]]
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[[Category: Xie W]]
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[[Category: Zeng, H]]
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[[Category: Zeng H]]
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[[Category: Deamination]]
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[[Category: Gsda]]
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[[Category: Hydrolase]]
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[[Category: Purine metabolism]]
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Current revision

The structure of the Arabidopsis thaliana guanosine deaminase mutant E82Q complex with guanosine

PDB ID 7dc9

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