7dow
From Proteopedia
(Difference between revisions)
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==The structure of the Arabidopsis thaliana guanosine deaminase in reaction with 7-deazaguansoine== | ==The structure of the Arabidopsis thaliana guanosine deaminase in reaction with 7-deazaguansoine== | ||
| - | <StructureSection load='7dow' size='340' side='right'caption='[[7dow]]' scene=''> | + | <StructureSection load='7dow' size='340' side='right'caption='[[7dow]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DOW FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7dow]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DOW FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dow OCA], [https://pdbe.org/7dow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dow RCSB], [https://www.ebi.ac.uk/pdbsum/7dow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dow ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HD3:2-azanyl-7-[(2R,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-3H-pyrrolo[2,3-d]pyrimidin-4-one'>HD3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dow OCA], [https://pdbe.org/7dow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dow RCSB], [https://www.ebi.ac.uk/pdbsum/7dow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dow ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GSDA_ARATH GSDA_ARATH] Catalyzes the hydrolytic deamination of guanosine, producing xanthosine and ammonia. Deaminates exclusively guanosine and 2'-deoxyguanosine but no other aminated purines, pyrimidines, or pterines. Deamination of guanosine by GSDA is the only source of xanthosine production in Arabidopsis.<ref>PMID:24130159</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Deaminase 3D structures|Deaminase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Arabidopsis thaliana]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Jia Q]] | [[Category: Jia Q]] | ||
[[Category: Xie W]] | [[Category: Xie W]] | ||
[[Category: Zeng H]] | [[Category: Zeng H]] | ||
Current revision
The structure of the Arabidopsis thaliana guanosine deaminase in reaction with 7-deazaguansoine
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