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7emg

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Current revision (16:56, 29 November 2023) (edit) (undo)
 
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<StructureSection load='7emg' size='340' side='right'caption='[[7emg]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='7emg' size='340' side='right'caption='[[7emg]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7emg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EMG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7emg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EMG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EMG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.449&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7emg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7emg OCA], [https://pdbe.org/7emg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7emg RCSB], [https://www.ebi.ac.uk/pdbsum/7emg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7emg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7emg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7emg OCA], [https://pdbe.org/7emg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7emg RCSB], [https://www.ebi.ac.uk/pdbsum/7emg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7emg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/A0A0G8B235_SERMA A0A0G8B235_SERMA]] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.[ARBA:ARBA00002607][RuleBase:RU366074]
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[https://www.uniprot.org/uniprot/A0A0G8B235_SERMA A0A0G8B235_SERMA] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.[ARBA:ARBA00002607][RuleBase:RU366074]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bai, Y P]]
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[[Category: Serratia marcescens]]
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[[Category: Wang, T]]
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[[Category: Bai YP]]
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[[Category: Zheng, Y C]]
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[[Category: Wang T]]
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[[Category: Carbonyl reductase]]
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[[Category: Zheng YC]]
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[[Category: Nadp+ complex]]
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[[Category: Oxidoreductase]]
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Current revision

Carbonyl Reductase Variant 4 (R123C/L209P/F183Y/V61K) from Serratia marcescens complexed with NADP+

PDB ID 7emg

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