This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7ev0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:04, 29 November 2023) (edit) (undo)
 
Line 1: Line 1:
==Crystal structure of pepsin cleaved C-terminal half of lactoferrin at 2.7A resolution==
==Crystal structure of pepsin cleaved C-terminal half of lactoferrin at 2.7A resolution==
-
<StructureSection load='7ev0' size='340' side='right'caption='[[7ev0]]' scene=''>
+
<StructureSection load='7ev0' size='340' side='right'caption='[[7ev0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EV0 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7ev0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EV0 FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ev0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ev0 OCA], [https://pdbe.org/7ev0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ev0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ev0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ev0 ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ev0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ev0 OCA], [https://pdbe.org/7ev0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ev0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ev0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ev0 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>
 +
 +
==See Also==
 +
*[[Lactoferrin|Lactoferrin]]
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ahmad MI]]
[[Category: Ahmad MI]]

Current revision

Crystal structure of pepsin cleaved C-terminal half of lactoferrin at 2.7A resolution

PDB ID 7ev0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7ev0"
Personal tools