This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7xfy
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution.== | ==Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution.== | ||
| - | <StructureSection load='7xfy' size='340' side='right'caption='[[7xfy]]' scene=''> | + | <StructureSection load='7xfy' size='340' side='right'caption='[[7xfy]], [[Resolution|resolution]] 2.67Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6jx8 6jx8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XFY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XFY FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7xfy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6jx8 6jx8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XFY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XFY FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xfy OCA], [https://pdbe.org/7xfy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xfy RCSB], [https://www.ebi.ac.uk/pdbsum/7xfy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xfy ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.67Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6NA:HEXANOIC+ACID'>6NA</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xfy OCA], [https://pdbe.org/7xfy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xfy RCSB], [https://www.ebi.ac.uk/pdbsum/7xfy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xfy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Camelus dromedarius]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Maurya A]] | [[Category: Maurya A]] | ||
Current revision
Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution.
| |||||||||||
