7xlo
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the Catalytic Domain of Inosine Monophosphate Dehydrogenase (IMPDH) from Methanocaldococcus jannaschii== | ==Crystal Structure of the Catalytic Domain of Inosine Monophosphate Dehydrogenase (IMPDH) from Methanocaldococcus jannaschii== | ||
| - | <StructureSection load='7xlo' size='340' side='right'caption='[[7xlo]]' scene=''> | + | <StructureSection load='7xlo' size='340' side='right'caption='[[7xlo]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XLO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XLO FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7xlo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XLO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XLO FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xlo OCA], [https://pdbe.org/7xlo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xlo RCSB], [https://www.ebi.ac.uk/pdbsum/7xlo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xlo ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xlo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xlo OCA], [https://pdbe.org/7xlo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xlo RCSB], [https://www.ebi.ac.uk/pdbsum/7xlo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xlo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IMDH_METJA IMDH_METJA] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Methanocaldococcus jannaschii]] | ||
[[Category: Balaram H]] | [[Category: Balaram H]] | ||
[[Category: Bellur A]] | [[Category: Bellur A]] | ||
[[Category: Sharma P]] | [[Category: Sharma P]] | ||
Current revision
Crystal Structure of the Catalytic Domain of Inosine Monophosphate Dehydrogenase (IMPDH) from Methanocaldococcus jannaschii
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