1hp3

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Current revision (18:38, 29 November 2023) (edit) (undo)
 
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==C-TERMINAL TRUNCATION OF OMEGA-ATRACOTOXIN-HV2A (CT-HV2A)==
==C-TERMINAL TRUNCATION OF OMEGA-ATRACOTOXIN-HV2A (CT-HV2A)==
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<StructureSection load='1hp3' size='340' side='right'caption='[[1hp3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1hp3' size='340' side='right'caption='[[1hp3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hp3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HP3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hp3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hadronyche_versuta Hadronyche versuta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HP3 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1g9p|1g9p]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hp3 OCA], [https://pdbe.org/1hp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1hp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hp3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hp3 OCA], [https://pdbe.org/1hp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hp3 RCSB], [https://www.ebi.ac.uk/pdbsum/1hp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hp3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE]] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>
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[https://www.uniprot.org/uniprot/TOT2A_HADVE TOT2A_HADVE] Potent inhibitor of insect (bee brain), but not mammalian (rat trigeminal neurons), voltage-gated calcium channels (Cav). As for omega-AcTx-Hv1a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops, followed by death.<ref>PMID:16330063</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hadronyche versuta]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: King, G F]]
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[[Category: King GF]]
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[[Category: Wang, X H]]
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[[Category: Wang X-H]]
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[[Category: Cystine knot]]
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[[Category: Toxin]]
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Current revision

C-TERMINAL TRUNCATION OF OMEGA-ATRACOTOXIN-HV2A (CT-HV2A)

PDB ID 1hp3

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