1nb1

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==High resolution solution structure of kalata B1==
==High resolution solution structure of kalata B1==
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<StructureSection load='1nb1' size='340' side='right'caption='[[1nb1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1nb1' size='340' side='right'caption='[[1nb1]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1nb1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oldenlandia_affinis Oldenlandia affinis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NB1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1nb1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oldenlandia_affinis Oldenlandia affinis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NB1 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kal|1kal]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nb1 OCA], [https://pdbe.org/1nb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nb1 RCSB], [https://www.ebi.ac.uk/pdbsum/1nb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nb1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nb1 OCA], [https://pdbe.org/1nb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nb1 RCSB], [https://www.ebi.ac.uk/pdbsum/1nb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nb1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF]] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref>
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[https://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref>
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oldenlandia affinis]]
[[Category: Oldenlandia affinis]]
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[[Category: Craik, D J]]
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[[Category: Craik DJ]]
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[[Category: Daly, N L]]
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[[Category: Daly NL]]
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[[Category: Plan, M R]]
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[[Category: Plan MR]]
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[[Category: Rosengren, K J]]
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[[Category: Rosengren KJ]]
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[[Category: Waine, C]]
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[[Category: Waine C]]
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[[Category: Antibiotic]]
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[[Category: Cck]]
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[[Category: Cyclic backbone]]
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[[Category: Cyclotide]]
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[[Category: Cystine knot]]
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[[Category: Insecticidal]]
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Revision as of 18:53, 29 November 2023

High resolution solution structure of kalata B1

PDB ID 1nb1

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