|
|
| Line 3: |
Line 3: |
| | <SX load='5o4u' size='340' side='right' viewer='molstar' caption='[[5o4u]], [[Resolution|resolution]] 4.20Å' scene=''> | | <SX load='5o4u' size='340' side='right' viewer='molstar' caption='[[5o4u]], [[Resolution|resolution]] 4.20Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[5o4u]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O4U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5O4U FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5o4u]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O4U FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5o4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o4u OCA], [http://pdbe.org/5o4u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o4u RCSB], [http://www.ebi.ac.uk/pdbsum/5o4u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o4u ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2Å</td></tr> |
| | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o4u OCA], [https://pdbe.org/5o4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o4u RCSB], [https://www.ebi.ac.uk/pdbsum/5o4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o4u ProSAT]</span></td></tr> |
| | </table> | | </table> |
| | == Function == | | == Function == |
| - | [[http://www.uniprot.org/uniprot/A0A0B4ZYM1_PYRFU A0A0B4ZYM1_PYRFU]] Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.[RuleBase:RU361282] | + | [https://www.uniprot.org/uniprot/A0A0B4ZYM1_PYRFU A0A0B4ZYM1_PYRFU] Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.[RuleBase:RU361282] |
| | <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| | == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
| Line 25: |
Line 26: |
| | </SX> | | </SX> |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Pyrococcus furiosus dsm 3638]] | + | [[Category: Pyrococcus furiosus DSM 3638]] |
| - | [[Category: Daum, B]] | + | [[Category: Daum B]] |
| - | [[Category: Vonck, J]] | + | [[Category: Vonck J]] |
| - | [[Category: Archaellar flagellum glycoprotein helical filament]]
| + | |
| - | [[Category: Cell adhesion]]
| + | |
| Structural highlights
Function
A0A0B4ZYM1_PYRFU Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.[RuleBase:RU361282]
Publication Abstract from PubMed
The archaellum is the macromolecular machinery that Archaea use for propulsion or surface adhesion, enabling them to proliferate and invade new territories. The molecular composition of the archaellum and of the motor that drives it appears to be entirely distinct from that of the functionally equivalent bacterial flagellum and flagellar motor. Yet, the structure of the archaellum machinery is scarcely known. Using combined modes of electron cryo-microscopy (cryoEM), we have solved the structure of the Pyrococcus furiosus archaellum filament at 4.2 A resolution and visualise the architecture and organisation of its motor complex in situ. This allows us to build a structural model combining the archaellum and its motor complex, paving the way to a molecular understanding of archaeal swimming motion.
Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery.,Daum B, Vonck J, Bellack A, Chaudhury P, Reichelt R, Albers SV, Rachel R, Kuhlbrandt W Elife. 2017 Jun 27;6. pii: e27470. doi: 10.7554/eLife.27470. PMID:28653905[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Daum B, Vonck J, Bellack A, Chaudhury P, Reichelt R, Albers SV, Rachel R, Kuhlbrandt W. Structure and in situ organisation of the Pyrococcus furiosus archaellum machinery. Elife. 2017 Jun 27;6. pii: e27470. doi: 10.7554/eLife.27470. PMID:28653905 doi:http://dx.doi.org/10.7554/eLife.27470
|
