This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3qe4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='3qe4' size='340' side='right'caption='[[3qe4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3qe4' size='340' side='right'caption='[[3qe4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3qe4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QE4 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3qe4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QE4 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4CF:4-CYANO-L-PHENYLALANINE'>4CF</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ag6|2ag6]], [[1zh0|1zh0]], [[1zh6|1zh6]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4CF:4-CYANO-L-PHENYLALANINE'>4CF</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0389, TyrRS, tyrS ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qe4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qe4 OCA], [https://pdbe.org/3qe4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qe4 RCSB], [https://www.ebi.ac.uk/pdbsum/3qe4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qe4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qe4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qe4 OCA], [https://pdbe.org/3qe4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qe4 RCSB], [https://www.ebi.ac.uk/pdbsum/3qe4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qe4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/SYY_METJA SYY_METJA]] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref>
+
[https://www.uniprot.org/uniprot/SYY_METJA SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 28: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 43067]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Tyrosine--tRNA ligase]]
+
[[Category: Methanocaldococcus jannaschii]]
-
[[Category: Ahmad, I]]
+
[[Category: Ahmad I]]
-
[[Category: Jahnz, M]]
+
[[Category: Jahnz M]]
-
[[Category: Schultz, P G]]
+
[[Category: Schultz PG]]
-
[[Category: Spraggon, G]]
+
[[Category: Spraggon G]]
-
[[Category: Young, D D]]
+
[[Category: Young DD]]
-
[[Category: Young, T S]]
+
[[Category: Young TS]]
-
[[Category: Evolved trna synthetase]]
+
-
[[Category: Ligase]]
+
-
[[Category: Trna]]
+
-
[[Category: Trna synthetase evolved to bind unnatural amino acid]]
+

Revision as of 08:13, 6 December 2023

An evolved aminoacyl-tRNA Synthetase with atypical polysubstrate specificity

PDB ID 3qe4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools