1y58
From Proteopedia
(Difference between revisions)
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==The structure of a lactoferricinB derivative bound to micelles== | ==The structure of a lactoferricinB derivative bound to micelles== | ||
| - | <StructureSection load='1y58' size='340' side='right'caption='[[1y58 | + | <StructureSection load='1y58' size='340' side='right'caption='[[1y58]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1y58]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y58 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1y58]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y58 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y58 OCA], [https://pdbe.org/1y58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y58 RCSB], [https://www.ebi.ac.uk/pdbsum/1y58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y58 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y58 OCA], [https://pdbe.org/1y58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y58 RCSB], [https://www.ebi.ac.uk/pdbsum/1y58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y58 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Nguyen | + | [[Category: Nguyen LT]] |
| - | [[Category: Schibli | + | [[Category: Schibli DJ]] |
| - | [[Category: Vogel | + | [[Category: Vogel HJ]] |
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Current revision
The structure of a lactoferricinB derivative bound to micelles
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