5oa2

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Current revision (09:38, 6 December 2023) (edit) (undo)
 
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<StructureSection load='5oa2' size='340' side='right'caption='[[5oa2]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='5oa2' size='340' side='right'caption='[[5oa2]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5oa2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OA2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5OA2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5oa2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OA2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9PW:[4-[[1-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-4-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]-1,2,3-triazol-4-yl]methoxymethyl]phenyl]-oxidanyl-oxidanylidene-azanium'>9PW</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAS2, YLR343W, L8300.5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9PW:[4-[[1-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-4-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]-1,2,3-triazol-4-yl]methoxymethyl]phenyl]-oxidanyl-oxidanylidene-azanium'>9PW</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5oa2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oa2 OCA], [http://pdbe.org/5oa2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oa2 RCSB], [http://www.ebi.ac.uk/pdbsum/5oa2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oa2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5oa2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oa2 OCA], [https://pdbe.org/5oa2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5oa2 RCSB], [https://www.ebi.ac.uk/pdbsum/5oa2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5oa2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GAS2_YEAST GAS2_YEAST]] Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly.<ref>PMID:17189486</ref> <ref>PMID:17397106</ref>
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[https://www.uniprot.org/uniprot/GAS2_YEAST GAS2_YEAST] Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly.<ref>PMID:17189486</ref> <ref>PMID:17397106</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Aalten, D Van]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Castro-Lopez, J]]
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[[Category: Castro-Lopez J]]
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[[Category: Delso, I]]
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[[Category: Delso I]]
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[[Category: Fang, W]]
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[[Category: Fang W]]
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[[Category: Gomollon-Bel, F]]
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[[Category: Gomollon-Bel F]]
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[[Category: Hurtado-Guerrero, R]]
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[[Category: Hurtado-Guerrero R]]
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[[Category: Merino, P]]
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[[Category: Merino P]]
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[[Category: Navratilova, I]]
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[[Category: Navratilova I]]
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[[Category: Tejero, T]]
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[[Category: Tejero T]]
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[[Category: Valero-Gonzalez, J]]
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[[Category: Valero-Gonzalez J]]
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[[Category: Afgel4]]
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[[Category: Van Aalten D]]
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[[Category: Aspergillus fumigatus]]
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[[Category: Cell wall remodeling]]
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[[Category: Fungal cell wall]]
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[[Category: Glucanosyltransferase]]
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[[Category: Scgas2]]
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[[Category: Transferase]]
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[[Category: Transglycosylase]]
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Current revision

Crystal structure of ScGas2 in complex with compound 8

PDB ID 5oa2

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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