Tiotropium bromide

Tiotropium bromide, sold under the brand name Spiriva among others, is a long-acting bronchodilator (LAMA: long acting muscarinic antagonist) used in the management of chronic obstructive pulmonary disease (COPD) and asthma.<ref name="a10">[https://www.drugs.com/monograph/tiotropium.html "Tiotropium Bromide Monograph for Professionals".] Drugs.com. American Society of Health-System Pharmacists. Archived from the original on 14 October 2018. Retrieved 31 January 2019.</ref><ref name="a11">British national formulary : BNF 76 (76th ed.). Pharmaceutical Press. 2018. pp. 247–248. ISBN 9780857113382.</ref> Specifically it is used during periods of breathing difficulty to prevent them from getting worse, rather than to prevent them from happening.<ref name="a10">[https://www.drugs.com/monograph/tiotropium.html "Tiotropium Bromide Monograph for Professionals".] Drugs.com. American Society of Health-System Pharmacists. Archived from the original on 14 October 2018. Retrieved 31 January 2019.</ref> See also [https://en.wikipedia.org/wiki/Tiotropium_bromide Tiotropium_bromide].