Syntrophin

From Proteopedia

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*α-1-syntrophin
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*alpha-1-syntrophin
**[[1z86]] – mSyn PDZ domain – mouse - NMR <br />
**[[1z86]] – mSyn PDZ domain – mouse - NMR <br />
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**[[2pdz]] – mSyn PDZ domain + voltage-gated sodium channel peptide - NMR <br />
**[[2pdz]] – mSyn PDZ domain + voltage-gated sodium channel peptide - NMR <br />
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*β-2-syntrophin
+
*beta-1-syntrophin
 +
 
 +
**[[7pc4]] – hSyn PDZ domain 107-196 + TAX-1 peptide - human<br />
 +
**[[7p70]] – hSyn PDZ domain + HPV35-E6 peptide <br />
 +
 
 +
*beta-2-syntrophin
 +
 
 +
**[[2vrf]] – hSyn PDZ domain <br />
 +
 
 +
*gamma-1-syntrophin
 +
 
 +
**[[7qqn]] – hSyn PDZ domain 54-143 + TRPV3 peptide <br />
 +
**[[7pc7]] – hSyn PDZ domain + PTEN peptide <br />
 +
**[[7pc8]] – hSyn PDZ domain + RSK1 peptide <br />
 +
 
 +
*gamma-2-syntrophin
 +
 
 +
**[[7qql]] – hSyn PDZ domain 70-159 + RSK1 peptide <br />
-
**[[2vrf]] – Syn PDZ domain – human <br />
 
}}
}}
== References ==
== References ==

Revision as of 08:39, 12 December 2023

Mouse syntrophin PDZ domain (deepskyblue) complex with neuronal NOS (green) (PDB code 1qav)

Drag the structure with the mouse to rotate

3D Structures of syntrophin

Updated on 12-December-2023

References

  1. Bhat HF, Adams ME, Khanday FA. Syntrophin proteins as Santa Claus: role(s) in cell signal transduction. Cell Mol Life Sci. 2013 Jul;70(14):2533-54. doi: 10.1007/s00018-012-1233-9. Epub , 2012 Dec 21. PMID:23263165 doi:http://dx.doi.org/10.1007/s00018-012-1233-9
  2. Wu G, Ai T, Kim JJ, Mohapatra B, Xi Y, Li Z, Abbasi S, Purevjav E, Samani K, Ackerman MJ, Qi M, Moss AJ, Shimizu W, Towbin JA, Cheng J, Vatta M. alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption. Circ Arrhythm Electrophysiol. 2008 Aug;1(3):193-201. doi:, 10.1161/CIRCEP.108.769224. PMID:19684871 doi:http://dx.doi.org/10.1161/CIRCEP.108.769224
  3. Hillier BJ, Christopherson KS, Prehoda KE, Bredt DS, Lim WA. Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science. 1999 Apr 30;284(5415):812-5. PMID:10221915

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