8unh
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp== | |
| - | + | <StructureSection load='8unh' size='340' side='right'caption='[[8unh]], [[Resolution|resolution]] 3.21Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8unh]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UNH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8unh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8unh OCA], [https://pdbe.org/8unh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8unh RCSB], [https://www.ebi.ac.uk/pdbsum/8unh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8unh ProSAT]</span></td></tr> |
| - | [[Category: Gee | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/LOADL_BPT4 LOADL_BPT4] Forms the sliding-clamp-loader together with the small subunit (PubMed:10585481). Functions as an ATPase enzyme (PubMed:16800623, PubMed:18676368). The clamp loader holds the clamp in an open conformation and places it onto the DNA (PubMed:22194570, PubMed:18676368). 4 ATP molecules must bind to the sliding-clamp-loader before the latter can open the sliding clamp (PubMed:18676368). ATP hydrolysis triggers the detachment of the sliding clamp from the sliding-clamp-loader, freeing the sliding clamp to track along DNA (PubMed:18676368, PubMed:22194570).[HAMAP-Rule:MF_04162]<ref>PMID:10585481</ref> <ref>PMID:16800623</ref> <ref>PMID:18676368</ref> <ref>PMID:22194570</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia virus T4]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Gee LC]] | ||
| + | [[Category: Ghaffari-Kashani S]] | ||
| + | [[Category: Gorday K]] | ||
| + | [[Category: Huang Y]] | ||
| + | [[Category: Kuriyan J]] | ||
| + | [[Category: Luo X]] | ||
| + | [[Category: Marcus K]] | ||
| + | [[Category: O'Donnell M]] | ||
| + | [[Category: Subramanian S]] | ||
| + | [[Category: Zhang L]] | ||
Current revision
Cryo-EM structure of T4 Bacteriophage Clamp Loader with Sliding Clamp
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Categories: Escherichia virus T4 | Large Structures | Gee LC | Ghaffari-Kashani S | Gorday K | Huang Y | Kuriyan J | Luo X | Marcus K | O'Donnell M | Subramanian S | Zhang L
