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1qjj
From Proteopedia
(Difference between revisions)
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<StructureSection load='1qjj' size='340' side='right'caption='[[1qjj]], [[Resolution|resolution]] 1.86Å' scene=''> | <StructureSection load='1qjj' size='340' side='right'caption='[[1qjj]], [[Resolution|resolution]] 1.86Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QJJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [https://pdbe.org/1qjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [https://www.ebi.ac.uk/pdbsum/1qjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjj ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [https://pdbe.org/1qjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [https://www.ebi.ac.uk/pdbsum/1qjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Proteinase|Proteinase]] | + | *[[Proteinase 3D structures|Proteinase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | + | [[Category: Astacus astacus]] | |
| - | [[Category: Astacus | + | |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: Bode W]] |
| - | + | [[Category: Grams F]] | |
| - | [[Category: | + | [[Category: Stocker W]] |
| - | [[Category: | + | |
| - | + | ||
Current revision
Structure of astacin with a hydroxamic acid inhibitor
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