1uuw

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Current revision (12:59, 13 December 2023) (edit) (undo)
 
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<StructureSection load='1uuw' size='340' side='right'caption='[[1uuw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1uuw' size='340' side='right'caption='[[1uuw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uuw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UUW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uuw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UUW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1eg9|1eg9]], [[1ndo|1ndo]], [[1o7g|1o7g]], [[1o7h|1o7h]], [[1o7m|1o7m]], [[1o7n|1o7n]], [[1o7p|1o7p]], [[1o7w|1o7w]], [[1uuv|1uuv]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uuw OCA], [https://pdbe.org/1uuw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uuw RCSB], [https://www.ebi.ac.uk/pdbsum/1uuw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uuw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uuw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uuw OCA], [https://pdbe.org/1uuw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uuw RCSB], [https://www.ebi.ac.uk/pdbsum/1uuw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uuw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NDOB_PSEPU NDOB_PSEPU]] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. [[https://www.uniprot.org/uniprot/NDOC_PSEPU NDOC_PSEPU]] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. The beta subunit may be responsible for the substrate specificity of the enzyme.
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[https://www.uniprot.org/uniprot/NDOB_PSEPU NDOB_PSEPU] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus fluorescens putidus flugge 1886]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Naphthalene 1,2-dioxygenase]]
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[[Category: Pseudomonas putida]]
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[[Category: Eklund, H]]
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[[Category: Eklund H]]
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[[Category: Gibson, D T]]
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[[Category: Gibson DT]]
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[[Category: Karlsson, A]]
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[[Category: Karlsson A]]
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[[Category: Parales, J V]]
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[[Category: Parales JV]]
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[[Category: Parales, R E]]
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[[Category: Parales RE]]
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[[Category: Ramaswamy, S]]
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[[Category: Ramaswamy S]]
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[[Category: 2fe-2]]
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[[Category: Aromatic hydrocarbons catabolism]]
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[[Category: Dioxygenase]]
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[[Category: Enzyme-substrate complex]]
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[[Category: Iron]]
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[[Category: Iron-sulfur]]
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[[Category: Metal-binding]]
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[[Category: Nad]]
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[[Category: Non-heme iron dioxygenase]]
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[[Category: Oxidoreductase]]
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[[Category: Plasmid]]
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Current revision

NAPHTHALENE 1,2-DIOXYGENASE WITH NITRIC OXIDE BOUND IN THE ACTIVE SITE.

PDB ID 1uuw

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